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Table 3 Signaling pathways associated with differentially expressed proteins as identified by Pathway Studio

From: A comprehensive proteomic approach to identifying capacitation related proteins in boar spermatozoa

Signaling pathways

Overlapping entities

P-value

Metabolic Pathways

  

  Tricarboxylic acid cycle

SUCLA2, PDHB

0.002

  Glutathione metabolism

PHGPx, PRDX5

0.011

Cell Signaling Pathways

  

  Adipocytokine signaling

SUCLA2, APOA1, PDHB

0.008

   Insulin action

SUCLA2, APOA1, PDHB

0.012

  1. Differentially expressed proteins were entered into Pathway Studio to identify the corresponding signaling pathways that potentially regulate capacitation. Among the differentially expressed proteins (>3-fold) of before- and after-capacitation, at least 5 exhibited regulatory roles in single or more pathways simultaneously (P < 0.05).
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BMC Genomics

ISSN: 1471-2164

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