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Figure 7 | BMC Genomics

Figure 7

From: Unveiling nonessential gene deletions that confer significant morphological phenotypes beyond natural yeast strains

Figure 7

Annotations of the genes deleted in the heteroclite 36 homozygous mutants. (A) Hierarchical cluster analysis of the 13 GOs. The dendrogram was constructed with complete linkage with the distances of GOs. The colored GOs indicate the representative four GOs in Figure 7B. The asterisks denote the GOs with significant differences between the annotated genes and the natural strains with PC scores at P <0.05 after Bonferroni correction by MANOVA. (B) Distribution of PC scores. Blue, orange, and black circles indicate the natural strains, the gene deletion strains, and BY4743, respectively. Red, magenta, cyan, and green circles denote the gene deletion strains with genes annotated to the GO terms of “cellular response to heat” (GO:0034605), “polysome” (GO:00005844), “recombinational repair” (GO:0000725), and “protein acylation” (GO:0043543), respectively. Gray dashed lines indicate the percentile of P =0.05 after Bonferroni correction to detect the heteroclite strains by one-sample two-sided tests of normal distribution.

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