Figure 2

Distribution of human reads by gene type and other reads by organism. Each individual is represented by a number: 1–3 this study (whole plasma); 4–6 Huang et al.[28] (plasma exosomal RNAs). The library preparation method is indicated as follows: a = Illumina; b: NEB; c = Bioo Scientific). (A) 100% stacked columns illustrating the proportions of reads annotated to human genes, non-human microRNAs or unannotated. (B) The proportions of unannotated reads (from (a)) subsequently assigned to superkingdom or kingdom. (C) Bacterial reads assigned to Phyla (those comprising <0.5% in all samples are not illustrated). (D) The proportions of fungal reads by phyla. (E) The proportions of reads assigned to classes within the phylum Ascomycetes. (F) The proportions of reads assigned to orders within the class Sordariomycetes.