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Table 4 Comparison of biological processes altered in wrn-1 mutant or wild type C. elegans strains treated with vitamin C

From: Expression profile of Caenorhabditis elegans mutant for the Werner syndrome gene ortholog reveals the impact of vitamin C on development to increase life span

Down in wrn-1 mutant + vitamin C vs untreated wrn-1 mutant C. elegans strain

Category

Benjamini P-value

Genes

Locomotion

0.0081

K07D8.1, C29F4.1, W05B2.1, T10E10.2, T28C6.6, T10E10.6, F46B3.5, F38A3.2, F55C10.3, T01B10.2, T28C6.4, C44C10.1, T22A3.8, F13H6.1, C26C6.3, F30B5.1, ZK270.1, Y4C6B.2, ZK678.5, W05B2.6, T07H6.3, K07C10.1, W05B2.5, Y41E3.2

Anatomical structure development

0.0065

C29F4.1, T10E10.2, T10E10.6, C29E4.1, C09G5.4, F38A3.2, T01B10.2, C44C10.1, F37B4.2, T07H6.3, F52B11.4, W05B2.1, T22B3.1, F27C1.8, T28C6.6, F55C10.3, T28C6.4, T22A3.8, F30B5.1, F11G11.10, B0491.2, F11G11.12, ZK270.1, W05B2.6, Y41E3.2, W05B2.5

Up in wrn-1 mutant + vitamin C vs untreated wrn-1 mutant C. elegans strain

No significant category

  

Down in N2 + vitamin C vs untreated N2 C. elegans strain

Category

Benjamini P -value

Genes

Proteolysis

0.0408

T23F4.4, ZK1037.10, F53A9.2, K07B1.1, W07B8.4, T19D2.1, W01A8.6, C29F3.2, B0222.4, F47H4.10, F42A10.8, Y95B8A.1, R10H1.5, C07D10.4

Up in N2 + vitamin C vs untreated N2 C. elegans strain

No significant category

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