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Table 2 Correlation analyses of placental and cord plasma testosterone levels, and placental estradiol-17ß with validated sex-specific mRNA expression differences of specific genes

From: Human placental transcriptome shows sexually dimorphic gene expression and responsiveness to maternal dietary n-3 long-chain polyunsaturated fatty acid intervention during pregnancy

 

CDK6

PCNA

HDAC5

LRP6

 

PL_T

PL_E2/T

CP_T

PL_T

PL_E2/T

CP_T

PL_T

PL_E2/T

CP_T

PL_T

PL_E2/T

CP_T

Rs

−0.06

0.19

0.08

−0.13

−0.01

−0.03

−0.09

0.18

−0.17

−0.28

0.48

0.13

P

0.734

0.254

0.658

0.422

0.969

0.864

0.591

0.268

0.339

0.080

0.002

0.476

N

38

38

31

41

41

33

41

41

33

41

41

33

 

DVL1

FZD7

TGFB1

 
 

PL_T

PL_E2/T

CP_T

PL_T

PL_E2/T

CP_T

PL_T

PL_E2/T

CP_T

   

Rs

−0.25

0.32

0.01

0.07

0.06

−0.21

−0.14

0.11

−0.15

   

P

0.115

0.044

0.955

0.688

0.728

0.233

0.395

0.490

0.422

   

N

41

41

33

41

41

33

41

41

33

   
  1. CP_T, cord plasma testosterone; N, number of analyzed individual samples or subjects; P, P-value for the correlation; PL_E2/T, placental estradiol-17ß / testosterone ratio; PL_T, placental testosterone; Rs, Spearman-rho correlation coefficient. Bold data represent significant correlations (P < 0.05).