Figure 3
From: Omics technologies provide new insights into the molecular physiopathology of equine osteochondrosis
Investigation of type-VI collagen localization and chondrocyte organization. Upper Panel - Type-VI collagen localization by immunostaining. Both lesion types (OCD [f] and osteochondral defects (OC) [s]) were characterized by positively stained areas (arrows) indicative of cartilage dedifferentiation leading to the formation of local scar tissue (fibrocartilage). Lower Panel - Magnification views (x20) of animals OC1-OC4 showing chondrocyte clusters located surrounding ( s ) or close to the lesions ( c ), which may reflect a healing process is underway.