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Figure 6 | BMC Genomics

Figure 6

From: Characterization of age signatures of DNA methylation in normal and cancer tissues from multiple studies

Figure 6

Disruption of age-associated DNA methylation signature in cancer. (A D) Plots of DNA methylation patterns of normal age-associated loci affiliated with DIRAS3 (CG13697378, CG09118625, and CG24871743 in A), MBD4 (CG19235307 and CG18303397 in B), MYF5 (CG26207503 and CG21126707 in C), and PRR34 (CG26394940 and CG13269407 in D) in normal (blue) and cancer (red) samples. Blue or red lines are the linear (or nonlinear) regression results for normal or cancer samples, respectively. (E) Plots of DNA methylation patterns of tumor suppressor genes including SEMA3B, RRP22 and CDKN2B.

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