Functional categories | Duplicate with 25% top #CTCF/dvs. rest of duplicates | Non-duplicates with 25% top #CTCF/dvs. rest of non-duplicates |
---|---|---|
 | GO terms a (↑ or ↓b, P-value c) | GO terms (↑ or ↓b, P-value c) |
Molecular functions | ||
 | DNA binding (GO:0003677) (↑, P<0.05) | transferase activity, transferring phosphorus-containing groups (GO:0016772) (↑, P<10-7) |
 | transcription factor binding (GO:0008134) (↑, P<10-2) | hydrolase activity, acting on acid anhydrides (GO:0016817) (↑, P<10-4) |
 | SMAD binding (GO:0046332) (↑, P<0.05) | protein domain specific binding (GO:0019904) (↑, P<10-2) |
 | growth factor binding (GO:0019838) (↑, P<0.05) | substrate-specific transmembrane transporter activity (GO:0022891) (↑, P<10-4) |
 | kinase inhibitor activity (GO:0019210) (↑, P<0.05) | cytoskeletal protein binding (GO:0008092) (↑, P<10-7) |
 | peptidase inhibitor activity (GO:0030414) (↑, P<0.05) | phospholipid binding (GO:0005543) (↑, P<10-2) |
 | protein kinase regulator activity (GO:0019887) (↑, P<0.05) | identical protein binding (GO:0042802) (↑, P<10-8) |
 | transferase activity, transferring acyl groups (GO:0016746) (↑, P<0.05) | receptor binding (GO:0005102) (↑, P<10-9) |
 | transferase activity, transferring glycosyl groups (GO:0016757) (↓, P<0.05) | heat shock protein binding (GO:0031072) (↑, P<0.05) |
 | monooxygenase activity (GO:0004497) (↓, P<0.05) | oxidoreductase activity, acting on peroxide as acceptor (GO:0016684) (↑, P<10-2) |
Cellular components | ||
 | extracellular matrix (GO:0031012) (↑, P<10-6) | extracellular matrix (GO:0031012) (↑, P<10-3) |
 | intracellular (GO:0031012) (↑, P<0.05) | extracelluar space (GO:0005615) (↑, P<10-8) |
 | receptor complex (GO:0043235) (↑, P<0.05) | endomembrane system (GO:0012505) (↑, P<10-3) |
 |  | membrane-bounded vesicle (GO:0031988) (↑, P<0.05) |
 |  | cell surface (GO:0009986) (↑, P<10-4) |
 |  | cell projection (GO:0042995) (↑, P<0.05) |
 |  | midbody (GO:0030496) (↑, P<0.05) |
Biological processes | ||
 | response to organic substance (GO:0010033) (↑, P<0.05) | response to organic substance (GO:0010033) (↑, P<10-5) |
 | regulation of metabolic process (GO:0019222) (↑, P<10-3) | lipid metabolic process (GO:0006629) (↑, P<10-6) |
 | regulation of catalytic activity (GO:0050790) (↑, P<10-2) | defense response (GO:0006952) (↑, P<10-3) |
 | regulation of cellular process (GO:0050794) (↑, P<10-3) | response to other organism (GO:0051707) (↑, P<0.05) |
 | regulation of cellular component organization (GO:0051128) (↑, P<0.05) | carbohydrate metabolic process (GO:0005975) (↑, P<0.05) |
 | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process (GO:0006139) (↑, P<10-2) | response to drug (GO:0042493) (↑, P<10-3) |
 | macromolecule biosynthetic process (GO:0009059) (↑, P<10-3) | cell-cell signaling (GO:0007267) (↑, P<10-2) |
 | gene expression (GO:0010467) (↑, P<10-2) | cytoskeleton organization (GO:0007010) (↑, P<10-3) |
 | cellular biosynthetic process (GO:0044249) (↑, P<10-4) | regulation of developmental process (GO:0050793) (↑, P<10-4) |
 | programmed cell death (GO:0012501) (↑, P<10-2) | regulation of immune system process (GO:0002682) (↑, P<10-4) |