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Table 2 Comparison of common non-synonymous SNP densities between GWAS reported genes and drug targets

From: GWAS and drug targets

 

Drug Targets

GWAS reported genes

HGMD genes

All genes

Density of all non-synonymous SNPs

0.0155

0.0171

0.0166

0.0171

Density of Common non-synonymous SNPs

0.00169

P = 0.00171

P = 0.00232

0.00221

0.00179

0.00214

  1. 1P-value for Mann-Whitney test against the density of common non-synonymous SNPs for GWAS reported genes.2P-value for Mann-Whitney test against the density of common non-synonymous SNPs for all genes.