Figure 3

The maximum likelihood estimates for four marburgvirus samples from infected NHP. We found the estimated intra-host evolutionary rates for non-synonymous substitutions to be in similar range. In three samples, MAF-based and D _T measures differed for synonymous substitutions, due to increases in frequency of a single allele. In the fourth sample, MAF-based and D _T measures were identical and overlapped. The mean evolutionary rate, $〈{\overline{\mu }}_i〉$, is in 10^-3 substitutions/site/year and t ₀ is in days. The standard errors are the 95% confidence intervals via bootstrapping.