Figure 3From: Open adjacencies and k-breaks: detecting simultaneous rearrangements in cancer genomesOAR and CAE of adjacency sets from cancer genomes. (A) Distribution of OAR on 74 adjacency sets from TCGA genomes that were classified as stepwise (all (k >2)-breaks) or one-off (all (k = 2)-breaks) in [7]. (B) Correlation between OAR(Ã) and k ^ ( A ̃ ) , the estimated proportion of adjacencies originating in (k >2)-breaks, for 50 prostate cancer adjacency sets from [4]. Red dots represent one-off sets and green stepwise are stepwise sets. Dot size indicates number of adjacencies in the set. (C, D) The CAE for the corresponding datasets.Back to article page