Table 1 Fifty-five genes differentially expressed between FVPTCs and FAs and comparison with TN sample expression

gamma-aminobutyric acid (GABA) B receptor, 2

GABBR2

7.09

1.06E-07

8.51

2.99E-08

1.20

4.10E-01

neuronal cell adhesion molecule

NRCAM

4.09

1.64E-07

4.06

1.76E-07

-1.01

9.64E-01

extracellular matrix protein 1

ECM1

18.36

5.77E-07

15.49

1.28E-06

-1.19

6.44E-01

heparan sulfate 6-O-sulfotransferase 2

HS6ST2

5.07

8.60E-07

3.77

1.11E-05

-1.35

1.71E-01

retinoid X receptor, gamma

RXRG

13.16

8.69E-07

15.64

3.64E-07

1.19

6.08E-01

insulin-like growth factor 2 mRNA binding protein 2

IGF2BP2

5.88

1.10E-06

4.90

4.45E-06

-1.20

4.40E-01

cellular retinoic acid binding protein 2

CRABP2

4.48

1.18E-06

4.20

2.07E-06

-1.07

7.50E-01

high mobility group AT-hook 2

HMGA2

5.15

1.33E-06

3.17

8.64E-05

-1.62

3.91E-02

interaction protein for cytohesin exchange factors 1

IPCEF1

-6.48

1.39E-06

-3.55

1.32E-04

1.82

2.70E-02

G protein-coupled receptor 155

GPR155

-2.83

2.09E-06

-1.31

8.64E-02

2.16

4.76E-05

Purkinje cell protein 4

PCP4

-2.47

2.17E-06

-1.50

5.96E-03

1.65

9.10E-04

dipeptidyl-peptidase 10 (non-functional)

DPP10

3.85

2.22E-06

1.99

2.34E-03

-1.93

2.49E-03

low density lipoprotein receptor-related protein 4

LRP4

8.23

3.70E-06

13.56

2.22E-07

1.65

1.16E-01

chondroitin sulfate N-acetylgalactosaminyltransferase 1

CSGALNACT1

-3.34

4.06E-06

-1.13

5.01E-01

2.95

9.50E-06

fibronectin type III domain containing 4

FNDC4

3.65

5.75E-06

2.48

2.85E-04

-1.47

6.15E-02

leucine-rich repeat kinase 2

LRRK2

20.97

6.06E-06

31.24

1.27E-06

1.49

3.92E-01

odz, odd Oz/ten-m homolog 1 (Drosophila)

ODZ1

13.95

6.87E-06

13.63

7.66E-06

-1.02

9.54E-01

lipase, member H

LIPH

18.83

7.39E-06

20.52

5.19E-06

1.09

8.49E-01

glutamate receptor interacting protein 1

GRIP1

-2.52

7.61E-06

-1.24

1.66E-01

2.04

9.33E-05

slit homolog 1 (Drosophila)

SLIT1

6.12

8.81E-06

9.01

7.51E-07

1.47

1.83E-01

protocadherin 7

PCDH7

3.46

8.83E-06

2.96

4.20E-05

-1.17

4.26E-01

proteolipid protein 1

PLP1

10.00

8.88E-06

4.92

4.63E-04

-2.03

6.14E-02

SOGA family member 3

SOGA3

2.54

9.38E-06

2.44

1.59E-05

-1.04

7.81E-01

patched domain containing 4

PTCHD4

9.30

1.03E-05

3.03

7.04E-03

-3.07

4.90E-03

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosamine

GALNT7

3.57

1.04E-05

8.03

1.35E-08

2.25

7.59E-04

glutaminyl-peptide cyclotransferase

QPCT

6.05

1.18E-05

5.68

1.79E-05

-1.06

8.27E-01

transcription factor CP2-like 1

TFCP2L1

-4.40

1.42E-05

-1.80

2.95E-02

2.45

1.51E-03

cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)

CWH43

-4.73

1.47E-05

-2.32

4.77E-03

2.04

1.10E-02

pleiomorphic adenoma gene 1

PLAG1

5.46

1.47E-05

3.88

1.75E-04

-1.41

2.26E-01

UDP-galactose-4-epimerase

GALE

2.74

1.52E-05

2.39

8.06E-05

-1.15

4.04E-01

neurotrophic tyrosine kinase, receptor, type 3

NTRK3

3.64

1.75E-05

2.68

3.21E-04

-1.36

1.61E-01

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

KIT

-4.84

1.93E-05

-1.47

1.72E-01

3.30

2.53E-04

acid phosphatase, prostate

ACPP

2.41

2.59E-0

2.48

1.72E-05

1.03

8.34E-01

diacylglycerol kinase, iota

DGKI

-3.53

3.16E-05

-1.88

1.19E-02

1.87

9.87E-03

vitamin D (1,25- dihydroxyvitamin D3) receptor

VDR

2.62

3.26E-05

2.63

3.09E-05

1.00

9.79E-01

family with sequence similarity 70, member A

FAM70A

2.74

3.30E-05

1.05

7.91E-01

-2.61

3.66E-05

uncharacterized LOC100129434

LOC100129434

-2.60

3.63E-05

-1.37

8.73E-02

1.90

1.22E-03

spermatogenesis associated 18

SPATA18

2.70

4.41E-05

1.95

1.93E-03

-1.38

8.18E-02

retrotransposon gag domain containing 4

RGAG4

3.13

4.80E-05

4.19

3.16E-06

1.34

1.66E-01

zinc finger protein 521

ZNF521

2.72

5.44E-05

4.00

1.03E-06

1.47

4.63E-02

pleckstrin and Sec7 domain containing 3

PSD3

3.50

5.69E-05

8.64

5.67E-08

2.47

9.62E-04

synapse differentiation inducing 1

SYNDIG1

-2.67

5.72E-05

-1.47

5.38E-02

1.82

3.60E-03

LIM domain only 3 (rhombotin-like 2)

LMO3

2.66

5.86E-05

5.59

4.25E-08

2.10

6.13E-04

adhesion molecule with Ig-like domain 2

AMIGO2

2.87

5.90E-05

2.51

2.35E-04

-1.14

5.02E-01

RNA binding protein with multiple splicing 2

RBPMS2

-2.73

6.11E-05

1.01

9.51E-01

2.76

3.45E-05

integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)

ITGA2

2.72

6.37E-05

5.15

1.30E-07

1.89

2.75E-03

sodium channel, voltage-gated, type IV, alpha subunit

SCN4A

2.29

6.51E-05

2.70

8.15E-06

1.18

2.95E-01

neuro-oncological ventral antigen 1

NOVA1

3.86

7.79E-05

2.49

2.83E-03

-1.55

9.88E-02

SMAD family member 9

SMAD9

-3.03

7.91E-05

-1.18

4.60E-01

2.57

2.66E-04

Sciellin

SCEL

5.85

8.10E-05

6.23

5.50E-05

1.07

8.48E-01

SLC26A8

SLC26A8

2.71

8.28E-05

1.45

7.47E-02

-1.87

3.65E-03

serine-rich and transmembrane domain containing 1

SERTM1

-5.94

8.38E-05

-1.58

2.05E-01

3.76

9.96E-04

calpain 3 (p93)

CAPN3

2.23

8.41E-05

2.93

2.60E-06

1.32

8.34E-02

immunoglobulin superfamily, member 1

IGSF1

8.63

8.51E-05

9.28

5.97E-05

1.07

8.60E-01

primary ciliary dyskinesia protein 1

PCDP1

-2.17

8.74E-05

-1.23

1.91E-01

1.77

1.15E-03