Figure 2

Main candidate genes differentially expressed in CCs and involved in both cell and ZP morphologies as revealed by IPA software. (Red): overexpressed genes. (Green): underexpressed genes. (Gray): ZP genes. Genes are CASP9 (caspase 9), CCNA2 (cyclin A2), RAN (RAN, member RAS oncogene family), CDKN1A (cyclin-dependent kinase inhibitor 1A), CYP11A1 (cytochrome P450, family 11, subfamily A, polypeptide 1), GLB1 (galactosidase, beta 1), HBA1/HBA2 (hemoglobin, alpha 1/ hemoglobin, alpha 2), HBB (hemoglobin, beta), HDAC2 (histone deacetylase 2), HSP90B1 (heat shock protein 90, beta, member 1), LAMB1 (laminin, beta 1), PRDX2 (peroxiredoxin 2), SGCB (sarcoglycan, beta), TIE1 (tyrosine kinase with immunoglobulin-like and EGF-like domains 1), ZP1 (zona pellucida glycoprotein 1 (sperm receptor)), ZP2 (zona pellucida glycoprotein 2 (sperm receptor)), ZP3 (zona pellucida glycoprotein 3 (sperm receptor)), and ZPBP (zona pellucida binding protein).