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Table 1 The top 20 biological processes assigned to the development-regulating HOTAIR by LncRNA2Function.

From: LncRNA2Function: a comprehensive resource for functional investigation of human lncRNAs based on RNA-seq data

GO term

Background frequency

Sample frequency

P-value

Corrected

P-value

System development

3253/20447

38/74

1.63E-12

2.37E-08

Anatomical structure morphogenesis

1884/20447

28/74

2.45E-11

7.10E-08

Tissue development

1183/20447

23/74

1.33E-11

7.10E-08

Embryonic skeletal system development

120/20447

10/74

1.73E-11

7.10E-08

Anatomical structure development

3717/20447

39/74

2.07E-11

7.10E-08

Skeletal system development

388/20447

14/74

1.01E-10

2.44E-07

Organ morphogenesis

790/20447

18/74

2.89E-10

4.73E-07

Multicellular organismal development

3830/20447

38/74

2.56E-10

4.73E-07

Developmental process

4248/20447

40/74

2.93E-10

4.73E-07

Organ development

2271/20447

29/74

3.63E-10

5.27E-07

Skeletal system morphogenesis

189/20447

10/74

1.54E-09

1.72E-06

Multicellular organismal process

5336/20447

44/74

1.39E-09

1.72E-06

Single-multicellular organism process

5125/20447

43/74

1.51E-09

1.72E-06

Extracellular matrix organization

204/20447

10/74

3.23E-09

3.28E-06

Extracellular structure organization

205/20447

10/74

3.39E-09

3.28E-06

Head development

52/20447

6/74

3.26E-08

2.96E-05

Embryonic skeletal system morphogenesis

91/20447

7/74

3.86E-08

3.30E-05

Single-organism developmental process

3161/20447

31/74

4.39E-08

3.54E-05

Chordate embryonic development

557/20447

13/74

9.05E-08

6.57E-05

Embryo development ending in birth or egg hatching

564/20447

13/74

1.05E-07

7.23E-05