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Figure 4 | BMC Genomics

Figure 4

From: Comprehensive genome-wide transcription factor analysis reveals that a combination of high affinity and low affinity DNA binding is needed for human gene regulation

Figure 4

PBEM enrichment tests in type I and type II TF binding sites for three yeast ChIP-chip experiments. By using a serial version of BayesPI2+, the best representative PBEMs were inferred from yeast ChIP-chip experiments for ACE2, SWI4 and INO4, respectively. Expected P-values, dbA, and classification of type I and type II TF binding sites (unequal-length yeast intergenic region) were based on these predicted PBEMs. In the figure, enrichment of PBEMs in predicted type I, type II TF binding sites, and the rest of intergenic regions ('Other') are shown by bar plots, where T-values were obtained by a two-tailed t-test (i.e. TF binding affinity in type I versus that in type II TF binding, in type II versus that in "Other", and in type I versus that in type II TF binding).

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