Table 1 Area under the ROC curve (AUC) for DESeq and XBSeq under various conditions with different number of replicates (3 and 6 replicates), different number of differential expressed genes (500, 1500) and different level of fold change (1.5 fold and 3 fold). Fold change at 5 or higher yield AUC = 1.00 for all conditions.
From: Differential expression analysis of RNA sequencing data by incorporating non-exonic mapped reads
| Â | Â | DESeq | XBSeq | ||
|---|---|---|---|---|---|
Replicates per group | Â | Fold Change | Fold Change | ||
| Â | DEGs (%) | 1.5x | 3x | 1.5x | 3x |
3 | 10% | 0.90 | 1.00 | 0.90 | 1.00 |
| Â | 30% | 0.89 | 1.00 | 0.89 | 1.00 |
6 | 10% | 0.96 | 1.00 | 0.97 | 1.00 |
| Â | 30% | 0.96 | 1.00 | 0.96 | 1.00 |