Application of a hierarchical enzyme classification method reveals the role of gut microbiome in human metabolism

BMC Genomics

Table 3 Overall prediction accuracy of ECemble method.

EC Level	Number of Sequences	Correctly Predicted*	% Overall Accuracy	Classes	Model(s)	Average # of features per model
Level-0 (Enzymes)	193240 (64948)	188866 (62674)	97.74 (96.50)	2	1	14241
Level-1	62674	62167	99.19	6	1	5045
Level-2	62167	61721	99.28	51	6	811
Level-3	61721	60931	98.72	169	51	95
Level-4	60931	60199	98.80	1921	169	30

*Correctly predicted: Instances predicted by at least 2 of top 3 classifiers. Level-0 represents the model to predict if a protein sequence is an enzyme or not. Level 1-Level 4 represents corresponding levels of the EC number hierarchy.

ISSN: 1471-2164