Table 2 Summary of regulatory regions from FANTOM5 and ENCODE.
Regulatory Regions | Source | Technique | Institute | Length(bp) | Percent of human genome (%) |
|---|---|---|---|---|---|
Transcription promoter | FANTOM5 | CAGE | RIKEN | 3,833,500 | 0.12 |
Transcription enhancer | FANTOM5 | CAGE | RIKEN | 12,385,403 | 0.38 |
Transcription insulator | ENCODE | ChIP-seq | HudsonAlpha Institute for Biotechnology, Yale University, Harvard University | 81,713,060 | 3.52 |
Methylation region | ENCODE | Methylation 450 | HudsonAlpha Institute for Biotechnology | 19,517,834 | 0.60 |
Histone modification region | ENCODE | ChIP-seq | Broad institute, Massachusetts General Hospital, Harvard Medical School | 2,816,878,674 | |
Chromatin physical interaction regions | ENCODE | CHIA-PET | Genome Institute of Singapore, Stanford University | 1,288,430,643 | 39.83 |
DNA binding sites of protein | ENCODE | ChIP-seq | HudsonAlpha Institute for Biotechnology, Yale University, Harvard University | 380,355,257 | 11.76 |
Open chromatin regions (DNase I hypersensitive sites) | ENCODE | DNase-seq | Washington University, Duke University | 387,138,495 | 11.97 |
Open chromatin regions by FAIRE-seq | ENCODE | FAIRE-seq | Duke University, University of North Carolina at Chapel Hill, University of Texas at Austin, European Bioinformatics Institute, University of Cambridge | 448,557,442 | 13.87 |