Figure 1

Visualizing genomic alterations of bromo domain containing genes. The core of the plot reflects the phylogenetic relationships between bromo domain containing proteins estimated by the sequence similarity of their associated domains. The inner circle displays the expression fold-changes between tumors and healthy tissues. High expression in tumors is indicated in red, while low expression in tumors is shown in blue. The outer circle illustrates the proportion of tumors with 'deep loss' (blue) or 'high-level gain' (red) changes. Mutation rates are reflected by the outer stacked bar plots.