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Table 3 Analysis of fluorescence ratios of genes known to be involved in cancer invasion.

From: Defining signal thresholds in DNA microarrays: exemplary application for invasive cancer

Gene

Invasive signal

Non-invasive signal

Ratio

Confidence category

 

Array 1

Array 2

Array 1

Array 2

Array 1

Array 2

 

TIMP-1

1.70

0.92

0.25

0.30

6.9

3.1

A

TIMP-2

0.63

0.25

0.24

0.70

2.5

0.4

 

MMP-9

4.16

2.22

1.70

1.01

2.5

2.2

 

Ln-5, γ2

1.27

1.22

0.06

0.03

22.5

35.5

B

Integrin α3

0.24

0.16

0.12

0.06

2.0

2.8

 

Ln-5, β3

0.15

0.06

0.09

0.04

1.9

1.6

C

  1. Ratios were qualitatively assigned to confidence categories according to their level of expression. All ratios met p < 0.05. TM was 0.18 for array 1 and 0.09 for array 2.
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BMC Genomics

ISSN: 1471-2164

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