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Table 2 Gene Ontology categories shared by the two genes in pairs with a CD below 20 kbp

From: Inter-species differences of co-expression of neighboring genes in eukaryotic genomes

(A) highly correlated pairs

  

category

description

# pairs

h

molecular functions

GO:0005132

interferon-alpha/beta receptor ligand

2

h

 

GO:0005194

cell adhesion

2

h

 

GO:0008089

anterograde axon cargo transport

4

h

biological process

GO:0006954

inflammatory response

6

h

 

GO:0006955

immune response

3

h

 

GO:0007165

signal transduction

5

h

cellular component

GO:0005634

nucleus

5

h

 

GO:0005886

plasma membrane

5

h

 

GO:0005887

integral to plasma membrane

2

y

molecular functions

GO:0003735

structural cons tituent of ribosome

12 (1)

y

biological process

GO:0006412

protein biosynthesis

13 (1)

y

cellular component

GO:0005737

cytoplasm

12 (2)

(B) zero-correlated pairs

h

molecular functions

GO:0005200

cytoskeletal structural protein

3

h

 

GO:0008009

chemokine

2

h

 

GO:0008417

fucosyltransferase

2

h

 

GO:0015464

acetylcholine receptor

2

h

biological process

GO:0006954

inflammatory response

3

h

 

GO:0007048

oncogenesis

4

h

 

GO:0007165

signal transduction

8

h

cellular component

GO:0005882

intermediate filament

3

h

 

GO:0005886

plasma membrane

4

h

 

GO:0005887

integral to plasma membrane

5

(C) negatively correlated pairs

h

molecular functions

GO:0005624

membrane fraction

3

h

biological process

GO:0006508

proteolysis and peptidolysis

2

h

 

GO:0007165

signal transduction

2

h

cellular component

GO:0005624

membrane fraction

3

h

 

GO:0005887

integral to plasma membrane

2

  1. A 'h' and 'y' in the left column denotes that the pairs were from the human (Diette [26]) and yeast (Cho et al. [9]) dataset, respectively. In yeast, none pair shared the same category in the ZC and NC groups. A number in parentheses in the right column indicates the number of duplicated pairs.