Figure 2

Alignment of the PECACE domain with Slt70. Protein fold recognition was performed with the 3D-PSSM server. The NP358524 sequence (residues 31–145) from S. pneumoniae (PECACE domain) is aligned with Slt70 from E. coli (P03810, residues 478–616). Amino acids of Slt70 involved in the catalytic reaction and in ligand recognition are underlined while residues conserved in each alignment are highlighted in red. The structural prediction for S. pneumoniae PECACE domain was determined (H = helix, C = coil) while Slt70 secondary-structure information was obtained from PDB file 1QSA.