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Table 2 Rfam non-coding RNAs in CORG A + sign indicates that a sequence fragment from the corresponding species (hsa Homo sapiens, mmu Mus musculus, rno Rattus norvegicus, dre Danio rerio, tru Takifugu rubripes) is contained in the CORG CNB; indicates that a blast search for an orhologous sequence in the Ensemble database was unsuccessful; n.d. mean no descriptive Ensemble gene annotation. The CNBs containing mir-196a-2 are shifted compared to the known microRNA sequences, preventing the detection of the correct stem-loop structure. The B columns marks whether a candidate was identified by a blast search against the Rfam or microRNA Registry, the A column shows whether a hairpin structure was identified by RNAalifold.pRNAz is the p-value for being an evolutionary conserved RNA secondary structure element returned by RNAz.

From: Comparative promoter region analysis powered by CORG

CNB

B

A

p RNAz

ncRNA

hsa

mmu

rno

dre

tru

gene

119596

+

+

0.995

mir-34c

+

+

+

+

n.d. (BCT-4)

119607

+

+

0.938

      

mir-34b in hsa

119658

+

+

0.985

       

159914

+

+

0.998

mir-138-2

+

+

+

+

SLC12A3, n.d. in teleosts

159932

+

+

0.999

       

159939

+

+

0.998

       

194777

+

+

0.998

mir-196b

+

-

+

+

+

HOXA9, dre: HOXA9a and HOXA9b

194820

+

+

0.999

       

194839

+

+

0.999

       

194941

+

+

0.999

       

226470

+

+

0.999

mir-10a

+

+

+

+

+

HOXB4, dre: HOXB4a and HOXB4b

226514

+

+

0.999

       

226555

+

+

0.999

       

226677

+

-

0.004

       

238163

+

+

0.992

mir-10b

+

+

+

+

+

HOXD4, dre: HOXD4a, n.d in tru

238188

+

+

0.984

       

238265

+

+

0.994

       

391314

+

-

0.125

mir-196a-2

+

+

-

+

+

HOXC9, dre: HOXC9a

391315

+

-

0.999

       

391318

+

-

0.511

       

470004

+

-

0.218

U93

+

+

+

0

+

n.d.

110374

-

+

0.995

IRES ?

+

+

+

+

+

DGCR8

146100

-

+

0.891

 

+

+

+

+

0

Ptf1a

393794

-

+

0.999

IRE

+

+

+

+

+

SLCA1