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Table 5 The top 25 genes exhibiting decreased mRNA abundance 2 hours post activation.

From: Development and validation of a bovine macrophage specific cDNA microarray

Clone

E value

Accession No.

Gene Symbol

Gene

Fold Decrease

FDRmax

P value

C0006018h16

0.0

NM_031483

ITCH

Itchy homolog E3 ubiquitin protein ligase

-5.36

2.55E-10

2.79E-12

MARC_2BOV_14N13

e-151

XM_582744

IL16

Interleukin 16

-4.94

9.35E-10

1.41E-11

C0006011p15

0.0

NM_003400

XPO1

Exportin 1

-4.11

3.28E-03

4.70E-04

C0006011d04

e-112

NM_000199

SGSH

N-sulfoglucosamine sulfohydrolase

-4.05

4.14E-05

2.88E-06

C0005202b11

0.0

NM_006565

CTCF

CCCTC-binding factor

-3.83

9.04E-06

4.90E-07

C0006014p20

0.0

NM_005642

TAF7

TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa

-3.74

7.65E-09

1.61E-10

MARC_1BOV_107K4

0.0

XM_584158

CCR2

Chemokine (C-C motif) receptor 2

-3.70

4.81E-06

2.40E-07

C0005203a5

6.00E-54

NM_032804

C10orf22

Chromosome 10 open reading frame 22

-3.69

2.77E-04

2.68E-05

C0006005d04

0.0

XM_588702

UNG

Uracil-DNA glycosylase

-3.62

4.24E-10

5.00E-12

C0007385D18

0.0

BM087483

-

EST

-3.60

2.00E-03

2.63E-04

C0006007o03

e-153

NM_016046

EXOSC1

Exosome component 1

-3.51

6.69E-07

2.57E-08

C0006019m08

0.0

XM_868169

-

Hypothetical protein LOC616204

-3.51

8.67E-06

4.67E-07

C0005205c2

2.00E-70

NM_024939

RBM35B

RNA binding motif protein 35B

-3.50

7.22E-08

2.15E-09

C0005207d22

0.0

NM_013444

UBQLN2

Ubiquilin 2

-3.48

1.36E-08

3.13E-10

C0005198j2

7.00E-58

NM_139014

MAPK14

Mitogen-activated protein kinase 14 (p38)

-3.41

1.36E-08

3.15E-10

C0006005h08

0.0

NM_052911

ESCO1

Establishment of cohesion 1 homolog 1

-3.36

9.89E-06

5.48E-07

C0005202l16

4.00E-42

XM_545369

C6orf32

Chromosome 6 open reading frame 32

-3.32

2.43E-10

2.61E-12

MARC_2BOV_105E23

e-119

NM_153425

TRADD

TNFRSF1A-associated via death domain

-3.18

3.95E-07

1.45E-08

C0006007o20

e-111

NM_001001806

ZFP36L2

Zinc finger protein 36, C3H type-like 2

-3.18

3.22E-09

5.75E-11

C0005209h6

e-108

NM_006163

NFE2

Nuclear factor (erythroid-derived 2), 45kDa

-3.13

3.40E-06

3.27E-07

C0006019p19

e-106

XM_868699

TOB2

Transducer of ERBB2, 2

-3.13

8.37E-07

3.31E-08

C0005202g13

0.0

AV594592

-

EST

-3.11

7.31E-04

8.25E-05

C0005208j1

0.0

CB221804

-

EST

-3.10

6.65E-05

5.18E-06

C0006012f10

1.00E-67

NM_145037

FAM55C

Family with sequence similarity 55, member C

-3.08

1.03E-11

6.98E-14

C0005208h20

0.0

CB420023

-

EST

-3.01

1.67E-05

9.91E-07

  1. Summary of the top 25 genes exhibiting decreased mRNA abundance 2 hours post activation, including clone name, accession number, e-value and identity of the best BLAST match and average fold change. The P and FDRmax values denote the probability from the moderated t-test and the Benjamini and Hochberg false discovery rate values respectively from the analysis of the resting cell values compared to the average activated sample values (Pre v Post).