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Table 3 Comparison of the main Gene Ontology categories among the gene lists

From: A biological question and a balanced (orthogonal) design: the ingredients to efficiently analyze two-color microarrays with Confirmatory Factor Analysis

Gene Ontology: Level 3

A2780 vs. CP70 + C30 + C200

CP70 vs. C30 + C200

 
 

N° Genes (%) 1

N° Genes (%) 2

P

Biological Process

   

   Cellular physiological process

60 (81)

39 (78)

0.82

   Metabolism

43 (58)

29 (58)

1

   Regulation of cellular process

24 (32)

15 (30)

0.85

   Organismal physiological process

23 (31)

10 (20)

0.22

   Regulation of physiological process

22 (30)

16 (32)

0.84

   Cell communication

20 (27)

13 (26)

1

   Localization

18 (24)

10 (20)

0.66

   Response to stress

13 (18)

5 (10)

0.30

   Response to biotic stimulus

10 (14)

5 (10)

0.78

   Cell adhesion

10 (14)

3 (6)

0.36

   Negative regulation of biological process

9 (12)

5 (10)

0.78

   Response to external stimulus

9 (12)

3 (6)

0.36

   Morphogenesis

7 (9)

3 (6)

0.73

   Organ development

6 (8)

5 (10)

0.75

Molecular Function

   

   Protein binding

33 (40)

24 (40)

1

   Ion binding

27 (33)

15 (25)

0.35

   Nucleic acid binding

18 (22)

12 (20)

0.84

   Transferase activity

14 (17)

3 (5)

0.04 (1)3

   Transcription factor activity

8 (10)

3 (5)

0.36

   Receptor activity

7 (9)

11 (18)

0.12

   Nucleotide binding

7 (9)

4 (7)

0.76

   Hydrolase activity

6 (7)

9 (15)

0.17

   Enzyme inhibitor activity

6 (7)

4 (7)

1

   Receptor binding

5 (6)

5 (8)

0.74

  1. 1 74 genes with Gene Ontology annotation for biological process and 82 for molecular function; 2 50 genes with Gene Ontology annotation for biological process and 60 for molecular function; 3 FDR adjusted p-value.