Figure 2

[X]uniqMAP statistics based on EnsEMBL version 40. Figures (a) to (c) summarise the data for the intra-comparisons within the human (left) and mouse (right) genomes. (a) The plots with the distributions of the proportion of exonic regions shared by all transcripts within a gene indicate that for some genes with high number of splicing variants it may be impossible to find a region to target simultaneously all their transcripts. (b) Distributions of the proportion of unique 19-mers found for genes, excluding pseudogenes, with single (red) and multiple transcripts (cyan) show that most genes present a high degree of uniqueness, although for nearly 25% of human genes the level of uniqueness is poor, i.e. between 0 and 5%. (c) Graphs summarising the lengths of the longest unique fragments found for each gene (red) or individual transcripts (blue). (d) Statistics from the inter-species comparisons of the human and mouse unique regions. The histograms correspond to the proportion of unique positions shared between the two organisms with respect to the total number of unique positions within each one of them (left) and the distribution of the longest unique fragments shared between the gene pairs (right).