Figure 3

Dist ribution of 3' distances from probesets with the most discrepant signal intensity following TwoRA (absolute Δlog2IN >= 2). A&B, histograms of 3' locations from the probesets at large represented on the MOE430A chip (green) versus those showing at least 2 fold change in log2 signal intensity following TwoRA (increase/decrease in signal, red/blue respectively). (Solid line), DRG. (Dashed lines), SA. (Dotted lines), SN. Arrows indicate additional peaks in the distributions apart from that of the overall population. C, a box and whisker plot showing the 0% and 100% quantiles as whiskers, the 25% and 75% quantiles as boxes and the 50% quantile as horizontal dash within the box. The plot summarises the distributions shown in A and B. One the y-axis, (+) indicates increase in signal intensity following TwoRA, (-) indicates decrease in signal intensity following TwoRA. Note that for all plots, probesets locations are in base pairs and relative to the 3' end of targets.