Table 1 Genes differentially expressed in node positive versus node negative cervical tumors

Upregulated in node positive tumors

32134

DNAJC9

10q22.2

DnaJ (Hsp(40) homolog, subfamily C, member 9

1.35

Protein folding

824723

MRPS23

17q22

Mitochondrial ribosomal protein S23

1.33

Structural component of mitochondrial ribosome

144880

PLAC2

19p13.3

Placenta-specific 2

1.47

Unknown

840486

VWF

12p13.3

Von Willebrand factor

1.35

Coagulation

345957

CSTA

3q21

Cystatin A

2.24

Lysosomal proteinase inhibition

49860

PDK2

17q21.33

Pyruvate dehydrogenase kinase, isoenzyme 2

1.23

Anaerobe metabolism

359119

CKS2

9q22

CDC28 protein kinase regulatory subunit 2

1.25

Cell cycle regulation

321354

In multiple clusters

1.27

825012

MGC14151

17p13.1

Hypothetical protein MGC14151

1.29

796176

LSM3

3p25.1

Hypothetical protein LOC285378

1.31

MRNA splicing

825229

MRPL11

11q13.3

Mitochondrial ribosomal protein L11

1.24

Structural component of mitochondrial ribosome

50671

FLJ12716

4q35.1

FLJ12716 protein

1.24

50491

BAI3

6q12

Brain-specific angiogenesis inhibitor 3

1.37

Angiogenesis

129516

RCL1

9p24.1

RNA terminal phosphate cyclase-like 1

1.21

Maturation of 18S RNA

290607

NEK1

4q33

NIMA (never in mitosis gene a) – related kinase 1

1.32

DNA damage repair

128208

DKFZp586I1420

7p15.1

Hypothetical protein DKFZp586I1420

1.21

Downregulated in node positive tumors

210698

EPB41L4B

9q31

Erythrocyte membrane protein band 4.1 like 4B

0.71

Structural constituent of cytoskeleton

810391

HYAL1

3p21.3

Hyaluronglucosaminidase 1

0.62

Degradation of extracellular matrix components

1637282

HK2

2p13

Hexokinase 2

0.70

Glucose metabolism

320392

MBNL2

13q32.1

Muscleblind-like 2 (Drosophila)

0.70

MRNA splicing

767769

FLJ13291

16q22.1

Hypothetical protein FLJ13291

0.82

126519

KLF3

4p14

Krüppel-like factor 3 (basic)

0.83

Glucose metabolism, growth, apoptosis, angiogenesis

230100

In multiple clusters

0.76

347546

ERO1L

14q22.1

ERO1-like (S. cerevisiae)

0.76

Oxidative protein folding

131362

MSN

Xq11.2

Moesin

0.71

Cell-cell and -extracellular matrix interaction

137456

TBX3

12q24.1

T-box 3 (ulnar mammary syndrome)

0.74

Regulation of growth and developmental processes

755506

ANXA4

2p13

Annexin A4

0.72

Growth regulation, apoptosis, calcium signaling

284619

In multiple clusters

0.81

143661

NTN4

12q22

Netrin 4

0.71

Cell-cell and -extracellular matrix interaction

713469

MEF2A

15q26

Myocyte enhancer factor 2A

0.79

Growth factor related transcription, differentiation

251135

DDOST

1p36.1

Dolichyl-diphosphooligosaccharide-protein glycosyltransferase

0.72

Glycosylation, apoptosis