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Table 1 Definitive list of hh-related genes in C. elegans with prediction errors and expression summary.

From: Comprehensive analysis of gene expression patterns of hedgehog-related genes

Gene

ORF

Hog

ORF prediction errors

Expression

EST clone No.

OST clone No.

SAGE hit

Links

wrt-1

ZK1290.12

+

 

ND, PY

1

1

+

[11]

wrt-2

F52E4.6

  

ND, PY

1

2

+

[11]

wrt-3

F38E11.7

 

Merged with upstream ORF

ND, PY

1

1

+

[11]

wrt-4

ZK678.5

+

 

ND, PY

10

1

+

[11]

wrt-5

W03D2.5

  

ND, PY

4

4

+

[11, 14]

wrt-6

ZK377.1

+

 

ND, PY

4

2

+

[11]

wrt-7

ZK1037.10

+

N- and C-term. wrong

ND, PN

0

2

+

[11]

wrt-8

C29F3.2

+

 

ND, PY

3

1

+

[11]

wrt-9

B0344.2

 

was 2 separate ORFs, with wrong exons

Y

0

0

+

Fig. 2A

wrt-10

ZK1290.8

  

Y

1

2

+

Fig. 2A, B, C, Table 4

grd-1

R08B4.1

+

N-term. wrong

N, PY

5

0

+

[11]

grd-2

F46B3.5

+

N-term. wrong

N, PN

3

1

+

[11]

grd-3

W05E7.1

 

merged with grd-13

ND, PY

15

0

+

[11]

grd-4

T01B10.1

  

N

0

3

+

 

grd-5

F41E6.2

  

Y, PY

10

0

+

Fig. 2B, C, Table 2, 4, [11]

grd-6

T18H9.1

  

Y, PY

6

1

+

PVT neuron, un-identified cells, [11]

grd-7

F46H5.6

  

Y, PY

0

1

+

Fig. 2B, [11]

grd-8

C37C3.4

  

Y, PN

0

2

-

Table 5, [11]

grd-9

C04E6.6

 

N- and C-term. wrong

N, PN

0

0

+

 

grd-10

F09D12.1

  

Y

9

2

+

Fig. 1B

grd-11

K02E2.2

+

 

N

0

1

+

 

grd-12

F02D8.2

  

Y

3

2

+

Fig. 2C, Table 2

grd-13

W05E7.3

 

merged with grd-3

Y

4

0

+

Fig. 2B, C, Table 3

grd-14

T01B10.2

 

N-term. wrong

Y

10

3

+

Fig. 2A, B, C

grd-15

Y87G2A.15

 

N-term. wrong

Y

0

0

+

Un-identified cells in the head and tail

grd-16

Y69A2AL.1

 

ORF totally wrong, basically not present

Y

0

4

-

Fig. 1B, Table 5

grd-17 p

Y102A5c.34

  

ND

0

0

+

 

hog-1

W06B11.4

+

 

Y

1

3

+

Fig. 2C a few un-identified cells in the head

qua-1

T05C12.10

+

 

PY

11

2

+

[15]

grl-1

C24G6.7

  

Y

0

2

+

Table 5

grl-2

T16G1.8

  

Y

1

1

+

Table 5

grl-3

K03B8.7

  

N

0

0

+

 

grl-4

F42C5.7

 

N-term., 1. exon wrong

Y

5

2

+

Fig. 2A, B, C, Table 2, 4

grl-5

Y47D7A.5

  

Y

15

2

+

Fig. 2A, C

grl-6

K10C2.5

  

Y

0

3

+

Table 5

grl-7

T02E9.2

  

Y

24

1

+

Fig. 2B

grl-8

ZC487.5

  

Y

0

1

+

Fig. 2C, Table 5

grl-9

ZC487.4

  

Y

2

2

+

Table 3

grl-10

C26F1.5

  

Y

10

1

+

Fig. 2B, C, Table 2

grl-11

ZK512.9

  

Y

0

2

+

Table 3

grl-12

F28A12.2

 

N-term. too long

Y

1

0

+

Table 5

grl-13

F32D1.4

 

N-term. wrong prediction

Y

0

0

+

Table 5

grl-14

T03D8.4

  

Y

1

2

+

Table 4

grl-15

Y75B8A.20

  

Y

5

0

+

Fig. 2A, B, Table 2

grl-16

Y65B4BR.6

  

N

22

3

+

 

grl-17

C56A3.1

  

Y

0

1

+

Fig. 2A, C, Table 3, 5

grl-18

T05C3.4

 

N-term. wrong

Y

0

1

+

Table 5

grl-19

R02D3.6

  

Y

1

0

+

Excretory duct cell

grl-20

C23H5.9

  

N

22

2

+

 

grl-21

ZC168.5

  

Y

4

4

+

Fig. 2A

grl-22

W03A5.3

  

ND

0

1

+

 

grl-23

E02A10.2

  

N

0

2

+

 

grl-24

F11E6.2

  

N

2

0

+

 

grl-25

ZK643.8

 

N-term. wrong

Y

2

0

+

Table 2

grl-26

K02D7.6

 

C-term. exon missed

Y

1

0

-

Table 4

grl-27

F40C5.3

  

Y

1

2

+

Fig. 2B, Table 4

grl-28

T24A6.15

  

Y

0

2

+

Table 5

grl-29

T24A6.18

  

Y

0

0

-

Fig. 2C, Table 5

grl-30 p

T24A6.3

  

ND

0

3

-

 

grl-31

T24A6.19

  

Y

0

3

-

Table 2

grl-32 p

T24A6.21

 

wrongly merged with other ORF

ND

0

0

-

 

61 total (3 pseudo)

  

18 (30%) wrong prediction

47

36

43

54

<-expression positive totals

  1. The ORF prediction errors column briefly describes errors found in the gene prediction at the onset of the project; the expression column indicates whether expression was seen. The p after a gene name indicates pseudogenes: grd-17 (N-term. frameshift), grl-30 (N-term. frameshift), grl-32 (duplication of last two exons of grl-27). The Hog column indicates which genes have a Hint/Hog domain. Expression column key: Y, expression; N, no expression; ND, not determined, no transgenic line/PCR construct; PY, expression in previous work [11]; PN, no expression in previous work [11]. The EST column indicates how many EST clones were found for that gene, the OST column how many OSTs were obtained. The SAGE hit column summarizes SAGE data: a plus indicates at least one hit. The Links column cites previous relevant publications and provides links to figures and tables in this paper.