Figure 1From: Gene expression patterns that predict sensitivity to epidermal growth factor receptor tyrosine kinase inhibitors in lung cancer cell lines and human lung tumorsSensitivity to erlotinib in cell lines. Sensitivity to EGFR tyrosine kinase inhibitors was determined by treating cells with 1 μM erlotinib for 72 hours under serum-starved conditions. Apoptosis was assessed by integration of the sub-G1 peak and compared to cells treated with equal volume of vehicle (DMSO). Experiments were repeated in triplicate with error bars representing standard deviation. : denotes statistical significance (p < 0.05, two sided t-test for unequal variances).Back to article page