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Figure 3 | BMC Genomics

Figure 3

From: Gene expression patterns that predict sensitivity to epidermal growth factor receptor tyrosine kinase inhibitors in lung cancer cell lines and human lung tumors

Figure 3

Classification of two independent collections of resected adenocarcinomas. Panel A: Tumors samples banked at H. Lee Moffitt Cancer Center and Research Institute were used for extraction of total RNA for probe preparation and hybridized to U133A arrays. IHC scoring was performed as previously described [27]. Thatched boxes represent predictions of sensitivity. Panel B: Tumors samples banked at Duke University were used for extraction of total RNA for probe preparation and hybridized to U133 2.0 arrays. pEGFR scoring is reported on a 4 point scale (0-3+). The presence of activating mutations within EGFR is also reported. Sensitive predictions are represented by a thatched box.

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