Table 2 The result of vaccine candidates according to localization sites: outermembrane
gene | Cy3 signal | Cy5 signal | COG | product |
|---|---|---|---|---|
LA0049 | 471 | 478.2 | COG0840NT COG2202T | aerotaxis sensor receptor, flavoprotein |
LA0099 | 1,081 | 853.5 | - | hypothetical protein |
LA0166 | 2,149 | 1,113 | COG1196D | hypothetical protein |
LA0178 | 1,224 | 953.8 | COG0706U | 60Kd inner membrane protein |
LA0241 | 554.5 | 905.7 | COG1999R | SCO1/SenC family protein |
LA0253 | 755.8 | 559.2 | COG2849S | hypothetical protein |
LA0272 | 462.2 | 734.8 | - | hypothetical protein |
LA0301 | 787 | 771.8 | COG2885M | outer membrane protein OmpA family |
LA0330 | 554 | 397.3 | COG2366R | Penicillin G acylase precursor |
LA0339 | 1,060 | 1,185 | COG0584C | Glycerophosphoryl diester phosphodiesterase |
LA0365 | 1,290 | 1,959 | - | hypothetical protein |
LA0370 | 720.7 | 952.8 | - | hypothetical protein |
LA0378 | 692.5 | 560.3 | COG0457R | TPR-repeat-containing proteins |
LA0379 | 1,134 | 957 | - | hypothetical protein |
LA0410 | 3,451 | 3,604 | COG2834M | hypothetical protein |
LA0423 | 553 | 712.8 | COG2931Q | hypothetical protein |
LA0505 | 6,317 | 7,727 | COG1409R | probable glycosyl hydrolase |
LA0532 | 736.5 | 684.7 | - | hypothetical protein |
LA0568 | 434.8 | 435.3 | COG2067I | hypothetical protein |
LA0635 | 1,131 | 712.8 | - | S-layer-like array protein |
LA0678 | 973.3 | 952.5 | COG0840NT | Methyl-accepting chemotaxis protein mcpB |
LA0811 | 478.8 | 770.5 | - | hypothetical protein |
LA0818 | 481.3 | 946.8 | - | hypothetical protein |
LA0878 | 886.7 | 555.7 | COG0266L | DshA protein |
LA0940 | 1,467 | 1,026 | - | hypothetical protein |
LA0957 | 2,798 | 1,542 | COG1538MU | outer membrane efflux protein |
LA1009 | 764.8 | 887.7 | COG5009M | Penicillin-binding protein 1A |
LA1010 | 1,124 | 829 | - | putative outermembrane protein |
LA1087 | 376.5 | 536 | - | hypothetical protein |
LA1099 | 2,388 | 1,500 | COG3103T | hypothetical protein |
LA1100 | 2,901 | 2,796 | COG1538MU | outer membrane efflux protein |
LA1161 | 474.2 | 403 | COG2067I | long-chain fatty acid transport protein |
LA1174 | 615 | 423 | COG0834ET | amino acid ABC transporter, periplasmic amino acid-binding protein |
LA1192 | 616.3 | 545.3 | - | putative outermembrane protein |
LA1404 | 1,377 | 977 | - | putative outermembrane protein |
LA1412 | 1,034 | 640.3 | - | hypothetical protein |
LA1495 | 1,920 | 2,172 | - | putative outermembrane protein |
LA1501 | 558.2 | 545.7 | COG4775M COG5009M | hypothetical protein |
LA1507 | 1,615 | 1,747 | - | hypothetical protein |
LA1690 | 744.7 | 471.7 | COG0449M | hypothetical protein |
LA1733 | 1,418 | 1,557 | - | hypothetical protein |
LA1912 | 873.8 | 745 | - | putative outermembrane protein |
LA1917 | 595.5 | 535.3 | - | hypothetical protein |
LA1931 | 941.5 | 1,540 | - | putative outermembrane protein |
LA1987 | 909.3 | 994.5 | - | putative outermembrane protein |
LA1996 | 556.8 | 674 | - | hypothetical protein |
LA2024 | 2,594 | 2,079 | - | hypothetical protein |
LA2063 | 1,463 | 1,967 | - | hypothetical protein |
LA2094 | 548.2 | 380.3 | COG1716T | FHA-domain containing protein |
LA2126 | 1,223 | 979.7 | COG0616OU | Putative signal peptide peptidase sppA |
LA2215 | 1,045 | 679.2 | COG1196D COG1360N | Chemotaxis motB protein |
LA2238 | 420 | 464.7 | COG0726G | polysaccharide deacetylase |
LA2266 | 367.3 | 364.5 | - | putative outermembrane protein |
LA2267 | 886.2 | 1,542 | COG0457R | putative outermembrane protein |
LA2268 | 971.7 | 1,074 | - | putative outermembrane protein |
LA2295 | 4,445 | 6,689 | COG0532J COG4254S | LipL45 protein |
LA2318 | 813.2 | 673.8 | COG4775M | Predicted outer membrane protein |
LA2368 | 347.8 | 585 | COG1555L COG3156U COG0477GEPR COG0075E | type II secretion pathway related protein etpK-like protein |
LA2375 | 1,255 | 2,047 | COG1450NU | General secretory pathway protein D |
LA2377 | 377.5 | 418 | COG0739M | peptidase, M23/M37 family protein |
LA2395 | 847.3 | 1,736 | COG2815S | putative outermembrane protein |
LA2413 | 540.7 | 381.2 | COG0791M | Probable lipoprotein nlpC precursor |
LA2464 | 362 | 435.7 | COG3225N | gliding motility protein GldG |
LA2468 | 3,653 | 6,205 | COG1196D | hypothetical protein |
LA2510 | 1,230 | 846 | COG1452M | hypothetical protein |
LA2537 | 1,329 | 1,304 | - | hypothetical protein |
LA2538 | 624.2 | 606.5 | - | hypothetical protein |
LA2612 | 532.8 | 574 | COG3190N | flagellar protein required for flagellar formation |
LA2617 | 656.5 | 697.8 | - | hypothetical protein |
LA2656 | 1,128 | 637.2 | COG2968S | hypothetical protein |
LA2664 | 905.3 | 867.8 | COG1706N | flagellar P-ring protein precursor |
LA2672 | 662.3 | 1,116 | - | hypothetical protein |
LA2741 | 1,649 | 916.7 | - | hypothetical protein |
LA2742 | 814.8 | 524.2 | - | hypothetical protein |
LA2755 | 4,175 | 2,808 | COG0768M | probable penicillin-binding protein |
LA2757 | 1,213 | 1,270 | COG1792M | rod shape-determining protein mreC |
LA2800 | 665 | 1,591 | - | hypothetical protein |
LA2818 | 681.7 | 440.8 | - | hypothetical protein |
LA2857 | 506.7 | 516.5 | COG0596R | Predicted hydrolase or acyltransferase, alpha/beta hydrolase superfamily |
LA2949 | 407.5 | 460 | COG0265O | heat shock protein, HtrA1 |
LA3069 | 1,221 | 786.3 | - | hypothetical protein |
LA3091 | 995.5 | 879.7 | - | hypothetical protein |
LA3118 | 771.7 | 1,239 | COG0466O | hypothetical protein |
LA3149 | 608.3 | 421.8 | COG1629P | Hemin receptor |
LA3165 | 749.2 | 454.7 | COG4642S | conserved hypothetical protein with MORN repeat |
LA3353 | 432.2 | 698.2 | - | hypothetical protein |
LA3403 | 391.3 | 388.8 | - | hypothetical protein |
LA3434 | 724.7 | 625.7 | COG0860M | N-acetylmuramoyl-L-alanine amidase |
LA3440 | 915.5 | 864.3 | COG0237H | hypothetical protein |
LA3468 | 618 | 584.8 | COG1629P | probable TonB-dependent receptor |
LA3469 | 658.2 | 685.7 | COG3487P | iron-reglulated protein A |
LA3506 | 1,407 | 1,266 | COG0840NT | Methyl-accepting chemotaxis protein |
LA3552 | 1,652 | 2,900 | - | hypothetical protein |
LA3632 | 1,028 | 1,337 | COG1413C | PBS lyase HEAT-like repeat containing protein |
LA3681 | 463.5 | 459 | - | phage-related-like protein |
LA3744 | 1,318 | 840.2 | - | hypothetical protein |
LA3862 | 537.3 | 761.3 | COG0532J | hypothetical protein |
LA3872 | 385.3 | 648.8 | COG0616OU | Putative signal peptide peptidase sppA |
LA3938 | 589 | 1,026 | COG0457R | hypothetical protein |
LA3970 | 532.7 | 398.5 | - | hypothetical protein |
LA4070 | 9,764 | 5,630 | - | hypothetical protein |
LA4212 | 1,678 | 1,684 | - | hypothetical protein |
LA4227 | 2,465 | 1,953 | COG5621R | hypothetical protein |
LA4232 | 509.3 | 612.2 | COG2982M | hypothetical protein |
LA4261 | 485.7 | 612.5 | COG0451MG | UDP-glucose 4-epimerase |
LA4263 | 1,012 | 1,290 | - | hypothetical protein |
LA4285 | 726.3 | 791.2 | COG3858R | hypothetical protein |
LA4341 | 1,009 | 1,146 | COG0739M | Peptidase family M23/M37 |
LB018 | 1,549 | 1,589 | COG1635H | hypothetical protein |
LB025 | 371.8 | 382.5 | - | hypothetical protein |
LB050 | 344 | 533.3 | - | hypothetical protein |
LB056 | 443.5 | 523.8 | COG0457R | TPR-repeat-containing protein |
LB061 | 550.2 | 769.7 | COG3211R | hypothetical protein |
LB191 | 344.3 | 410 | COG1629P COG4771P | putative TonB-dependent outer membrane receptor protein |
LB199 | 917.3 | 925.2 | COG1629P | putative outermembrane protein |
LB258 | 552.5 | 1,082 | COG4870O | Cysteine protease |
LB277 | 1,634 | 984.3 | - | hypothetical protein |
LB279 | 1,115 | 804.3 | COG1629P | hypothetical protein |
LB328 | 1,591 | 2,672 | COG1360N COG2885M | outer membrane protein OmpA |
LB362 | 1,246 | 7,69 | - | hypothetical protein |