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Table 4 The result of vaccine candidates according to localization sites: innermembrane

From: In silico and microarray-based genomic approaches to identifying potential vaccine candidates against Leptospira interrogans

gene

Cy3 signal

Cy5 signal

COG

product

LA0238

662.5

433.2

COG1612O

cytochrome-c oxidase assembly factor ctaA

LA0250

651.2

738.8

COG4956R

TRAM family protein

LA0314

577.2

368

COG0168P

Trk system potassium uptake protein trkH

LA0550

1,353

886.5

COG0841V

NolG efflux transporter

LA0639

858.2

469.7

-

hypothetical protein

LA0650

870.7

628

COG0705R

Rhomboid family protein

LA0680

530.2

707.5

COG0004P

hypothetical protein

LA0960

760.7

452

-

hypothetical protein

LA1056

702.7

607.8

COG0840NT

hypothetical protein

LA1143

4,027

4,074

COG0341U

Preprotein translocase subunit SecF

LA1191

1,014

790.7

COG0840NT

Methyl-accepting chemotaxis protein

LA1283

902.2

1,162

COG0845M

hypothetical protein

LA1284

415.7

543

COG4591M

Lipoprotein releasing system transmembrane protein lolC

LA1321

374.8

860.8

COG4232OC

thiol:disulfide interchange protein DsbD

LA1397

722.8

672.3

COG1033R

putative Protein export membrane protein SecD/SecF

LA1435

612.2

524.3

COG0392S

hypothetical protein

LA1451

415.2

435.2

COG1183I

Phosphatidylglycerophosphate synthase

LA1471

3,360

7,809

COG3808C

Pyrophosphate-energized vacuolar membrane proton pump

LA1477

566.7

436.8

COG1519M

3-deoxy-D-manno-octulosonic-acid transferase

LA1535

521.5

685.5

-

hypothetical protein

LA1554

498.7

398.2

COG1502I

hypothetical protein

LA1695

4,493

2,360

-

CrcB-like protein

LA1958

2,663

1,551

COG0526OC

putative outermembrane protein

LA1979

483.8

657.8

COG0463M

Putative glycosyl transferase

LA1982

342.5

452

COG3307M

hypothetical protein

LA2050

411.3

848.8

COG0707M

UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

LA2250

10,742

9,624

-

Nuclease S1

LA2275

1,415

1,071

COG0586S

dedA protein

LA2320

1,319

1,496

COG0811U

biopolymer transport protein, putative

LA2604

464.3

448.7

-

hypothetical protein

LA2737

3,813

2,157

COG0204I

putative acyltransferase

LA2891

5,229

3,140

COG1055P

hypothetical protein

LA3072

1,970

1,665

COG0477GEPR

hypothetical protein

LA3110

1,262

2,371

COG2156P

potassium-transporting ATPase, C chain

LA3146

877

523.2

COG2076P

hypothetical protein

LA3577

1,618

1,198

COG1291N

motility protein A

LA3586

2,348

1,746

COG4270S

hypothetical protein

LA3754

667.3

449.7

COG0681U

Signal peptidase I

LA3777

497.3

539

COG0239D

Protein crcB homolog

LA3806

2,116

2,869

COG0004P

Probable ammonium transporter

LA3916

5,518

5,510

-

hypothetical protein

LA3926

967.8

1,802

COG0841V

transmembrane efflux pump protein

LA4062

1,326

2,138

-

hypothetical protein

LA4154

638.7

759

COG3225N

hypothetical protein

LA4155

1,140

1,015

COG1277R

probable permease of ABC transporter

LA4172

411

392.5

-

hypothetical protein

LA4228

559.5

627.8

COG4174R

Dipeptide transport system permease protein dppB

LA4233

409

985.7

COG1172G

hypothetical protein

LA4269

1,907

2,240

COG2207K COG0477GEPR

transcriptional regulator, AraC family

LB174

2,150

3,440

COG0501O

heat shock protein HtpX

LB281

5,026

2,708

COG0811U

transport protein ExbB