Further understanding human disease genes by comparing with housekeeping genes and other genes

BMC Genomics

Table 3 Comparison of the length of various parts of UEHGs, disease genes, and all other genes.

	UEHGs (n = 1400)	Disease (n = 1773)	Others (n = 10304)	P-value
Coding sequence length	1501 ± 38 1109	2205 ± 73 1537	1849 ± 15 1459	3.2E-09
Total exon length	2545 ± 48 2136	3250 ± 78 2557	2752 ± 18 2343	1.6E-06
Number of exons	10.7 ± 0.2 8	13.5 ± 0.3 10	9.9 ± 0.1 7	9.6E-07
Total intron length	35698 ± 1558 15588	60376 ± 2836 23528	54881 ± 1139 18540	0.012
5' UTR length	546 ± 22 238	582 ± 21 251	560 ± 8 245	0.55
3' UTR length	559 ± 21 247	569 ± 21 243	575 ± 8 254	0.86

For each row the first line gives the average value ± s.e.m, and the second line gives the median. UTR stands for untranslated region. Pair-wise rank sum tests are performed and only the largest P-values are listed in the last column.

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