Skip to main content

Table 1 Maximum LOD score in candidate regions

From: Genomewide high-density SNP linkage analysis of non-BRCA1/2 breast cancer families identifies various candidate regions and has greater power than microsatellite studies

CHR

Region

From

To

NPL

p value

PAR DOM

PAR REC

  

SNP

cM

SNP

cM

    

2

2p22.3

rs1054889

56

rs1167465

62

    

3

3p21.31p14.3

rs1014228

67

rs920891

70

2.19

0.014

0.74

NL

4

4p14q12

rs1046655

51

rs2538

64

2.01

0.02

1.31

1.12

7

7q21.11q21.3

rs2040902

95

rs722263

105

2.44

0.007

1.02

1.57

11

11q12.3q14.3

rs1525064

67

rs1404532

91

2.15

0.02

1

NL

14

14q13.1q21.3

rs2027338

34

rs1532202

43

1.89

0.03

1

NL

  1. LOD score values under the dominant (PAR DOM), recessive (PAR REC), and nonparametric (NPL) analysis with the p-values of the SNP-GWS in 19 BRCAX families using ALL frequencies. NL: no linkage (values < 1 in parametric analysis)
Back to article page

BMC Genomics

ISSN: 1471-2164

Contact us