Skip to main content

Table 1 Over-represented GO classes from the 'Molecular Function' and 'Biological Process' hierarchies observed among genes involved in fusion events

From: Denoising inferred functional association networks obtained by gene fusion analysis

GO Molecular Function Class Number of domains found Domains with GO Annotation Percentage in fusion events Percentage in all domains Log Odds Expectation
receptor activity 122299 720242 0.170 0.017 3.349
protein transporter activity 180926 720242 0.251 0.029 3.120
small protein conjugating activity 5566 720242 0.008 0.001 2.798
microtubule motor activity 2780 720242 0.004 0.001 1.797
channel or pore class transporter activity 11394 720242 0.016 0.009 0.832
transcription factor activity 185303 720242 0.260 0.161 0.675
site-specific recombinase activity 3732 720242 0.005 0.003 0.636
extracellular matrix structural constituent 1242 720242 0.002 0.001 0.634
group translocator activity 1742 720242 0.002 0.002 0.122
other classes 205258 720242 0.285   
GO Biological Process Class      
cell communication 25613 416772 0.061 0.010 2.674
regulation of cellular process 48082 416772 0.115 0.055 1.068
regulation of development 4082 416772 0.010 0.007 0.510
cellular physiological process 34681 416772 0.083 0.059 0.493
regulation of physiological process 205318 416772 0.493 0.356 0.468
other classes 98996 416772 0.238