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Table 4 Examples of down-regulated genes in DM semitendinosus.

From: Target genes of myostatin loss-of-function in muscles of late bovine fetuses

Gene

Gene name

Fold change

Homology

Tncc

Troponin C, cardiac/slow skeletal

6.22

94%

PLN

Phospholamban

5.48

98%

ALPHA-1COLLAGEN-a

Alpha-1 collagen type 1

5.22

98%

MYH7-a

Myosin, heavy polypeptide 7, cardiac muscle, beta

4.86

96%

TNNC1

Troponin C, slow

4.71

94%

Tpm3

Tropomyosin 3

3.38

94%

MYH7-b

Myosin, heavy polypeptide 7, cardiac muscle, beta

3.37

90%

TNNC1

Troponin C, slow

3.32

92%

COL3A1

Collagen, type III, alpha 1

2.98

96%

ALPHA-1COLLAGEN-b

Alpha-1 collagen type 1

2.97

98%

VIM

Vimentin

2.76

94%

COL1A2

Collagen, type I, alpha 2

2.64

84%

GPR72

G protein-coupled receptor 83

2.52

ND

S100A4

S100 calcium binding protein A4

2.38

92%

COL1A1

Collagen, type I, alpha 1

2.26

80%

GL004

Chromosome 2 open reading frame 33

2.25

94%

Fn1

Fibronectin 1

2.11

90%

MYL2

Myosin, light polypeptide 2, regulatory, cardiac, slow

2.08

92%

MRPL15

Mitochondrial ribosomal protein L15

2.01

84%

hypothLOC150928

Hypothetical LOC150928

2.01

98%

SERCA2

ATPase, CA++ transporting, cardiac muscle

2.00

94%

MB

Myoglobin

1.90

90%

  1. Genes were declared differentially expressed by SAM (FDR < 5‰) and by GeneANOVA with a p-value < 1‰ from dataset 2. Percentage homologies between spotted oligonucleotides and bovine sequences were determined using BLASTN and BLASTX searches. ND: none determined (unknown bovine sequence). -a, -b indicate two different oligonucleotides designed for a same gene.