Figure 1

Clustered heat maps for differentiation time-course experiments in three mouse ES cell lines: R1, J1, and V6.5. Expression values for 1,605 probe sets, corresponding to 1,327 transcription factor genes (according to protein domain analysis), were extracted from data from the MOE430A microarray for 11 time points from 0 hours to 14 days. The data for each cell line were mean-centered by probe set and by array, and clustered using Cluster 3.0 (University of Tokyo). Clusters were visualized using Java TreeView [72].