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Figure 6 | BMC Genomics

Figure 6

From: Human sterile alpha motif domain 9, a novel gene identified as down-regulated in aggressive fibromatosis, is absent in the mouse

Figure 6

SAMD9 reduces tumor size. A. Increased expression of SAMD9 reduced SW480 cell proliferation rate as detected by Brdu incorporation percent. B. Increased expression of SAMD9 reduced the invasion index of SW480 cells. C. Increased expression of SAMD9 increased caspase activity in SW480 cells. D and E. The tumor volume formed from SW480 xenografts was reduced with increased expression of SAMD9 when transplanted into nude mice (D) or Nod-scid mice (E).

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BMC Genomics

ISSN: 1471-2164

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