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Table 1 The top five non-redundant Gene Ontology (GO) terms in biological process which contain the most differentially expressed genes. Up or down, up- or down-regulation after infection, respectively; T, number of genes assigned to this the GO term; M, the subset of T genes that are represented on the microarray; C, the subset of M genes observed to vary in the analysis; Z, significance score

From: Genome-wide analysis of the interaction between the endosymbiotic bacterium Wolbachia and its Drosophila host

 

GO Term

T

M

C

Z

Up

Antimicrobial humoral response (sensu Protostomia)

70

20

6

7.4

 

Negative regulation of cell proliferation

42

10

3

5.3

 

Ion homeostasis

40

10

3

5.3

 

Larvae development (sensu Insecta)

54

14

3

4.3

 

Dorsal appendage formation

39

15

3

4.1

Down

Response to unfolded protein

50

15

6

12.6

 

Response to chemical stimulus

248

77

6

4.7

 

Tissue morphogenesis

78

16

2

3.7

 

RNA splicing

101

40

3

3.2

 

Positive regulation of transcription, DNA-dependent

102

34

2

2.2