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Table 1 GO categories with high promoter conservation. Terms of biological process are labeled as P, cellular component as C, molecular function as F.

From: Weak correlation between sequence conservation in promoter regions and in protein-coding regions of human-mouse orthologous gene pairs

GO term

Number of genes

P-value

P:development

649

0

P:regulation of transcription

602

1.67E-15

F:transcription factor activity

263

3.44E-15

P:transcription

640

4.11E-14

P:nervous system development

154

1.99E-10

P:organ development

213

2.30E-10

P:signal transduction

994

5.19E-10

F:DNA binding

628

3.19E-08

P:morphogenesis

212

9.78E-08

P:cell surface receptor linked signal transduction

363

2.23E-06

P:negative regulation of metabolism

107

1.02E-05

F:receptor binding

221

1.90E-05

P:cell-cell signaling

176

2.27E-05

F:cytoskeletal protein binding

137

4.97E-05

P:negative regulation of biological process

327

6.87E-05

F:ion channel activity

98

9.87E-05

C:extracellular matrix

111

0.000119

C:actin cytoskeleton

85

0.000164

P:cell differentiation

173

0.000179

P:cell adhesion

242

0.000182

P:cellular morphogenesis

111

0.000607

F:ion transporter activity

237

0.001493

P:protein amino acid phosphorylation

213

0.001593

P:ion transport

239

0.001825

F:protein kinase activity

220

0.002033

P:intracellular signaling cascade

431

0.006872

P:chromosome organization and biogenesis

105

0.007832

C:plasma membrane

608

0.008026