Transcriptional regulation by Poly(ADP-ribose) polymerase-1 during T cell activation

BMC Genomics

Table 1 PARP-1 dependent genes in T cells^a

^a Genes were classified as PARP-1 dependent genes when their expression was change by a factor of at least 1.5 (F-test<0.05) between Parp-1^+/+ and Parp-1^-/- cells in the microarrays analysis. ^bPositive regulation was considered when the expression of a particular gene was higher in the presence of PARP-1 than in its absence. Likewise, genes expressed at higher level in the absence of PARP-1 than in its presence were considered negatively regulated by PARP-1.

ISSN: 1471-2164