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Table 1 Co-expression of genes belonging to the same OXPHOS complex.

From: Transcriptional co-expression and co-regulation of genes coding for components of the oxidative phosphorylation system

  

CI

CII

CIII

CIV

CV

30% of genes

Total number of genes

Mouse GNF [28]

T-test p-value

3.206E-08

0.27071

0.17001

0.15739

0.00218

  
 

Complex

32%*

33%*

43%*

36%*

43%

  
 

All the rest

20%

20%

32%

27%

26%

  
 

Number of genes

26

3

6

7

10

22

74

Mouse U74A GNF [42]

T-test p-value

0.04179

0.13052

0.55088

0.02878

0.59082

  
 

Complex

33%

52%*

21%

42%*

25%

  
 

All the rest

29%

32%

23%

25%

23%

  
 

Number of genes

24

4

7

6

10

16

67

Human GNF [28]

T-test p-value

0.01723

0.30656

0.57973

0.71118

0.00054

  
 

Complex

27%

20%*

36%*

30%

58%

  
 

All the rest

24%

13%

33%

29%

37%

  
 

Number of genes

41

4

8

13

16

25

107

Human Stanford [43]

T-test p-value

0.07585

0.90503

0.24156

0.80409

0.02637

  
 

Complex

23%*

17%*

36%*

27%*

61%

  
 

All the rest

20%

15%

27%

25%

41%

  
 

Number of genes

30

3

8

6

10

17

74

All Datasets

T-test p-value

1.980E-07

0.03427

0.18684

0.02169

1.01E-05

  
 

Complex

28%

31%

34%

33%

48%

  
 

All the rest

23%

19%

29%

27%

33%

  
 

Number of genes

121

15

29

32

46

43

43

  1. We observed a co-expression for genes within the same complex at a tissue level. The table shows the results of the OXPHOS correlation test for different mouse and human tissue microarray datasets. 'All datasets' represent the results obtained by grouping all the datasets. T-test p-values represent the probability that genes within each complex do not preferentially co-express with genes of its same complex. 'Complex' percentage values represent the average percentage of genes of each complex that have expression similarities within 30% cutoff to genes in the complex labeled above. 'ALL the rest' represent the average percentage of genes within each complex that have expression patterns within the first 30% similarity in genes of any other complex. The 'Number of genes' represent the number of genes representing that complex in each microarray dataset. Asterisks, show cases in which the statistical test did not reach the significant cutoff but showed a trend of higher average percentages in subunits of the same complex than all the rest.