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Figure 1 | BMC Genomics

Figure 1

From: Sub-grouping and sub-functionalization of the RIFIN multi-copy protein family

Figure 1

RIFIN proteins overview. (A) Alignment of a selection of A and B-type RIFINs. Conserved cysteines are highlighted in red; shading according to conservation. (B) Schematic RIFIN sub-group characteristics: Overall domain organization and classification into subtypes. The 25 amino acid stretch present only in the semi-conserved domain of A-type RIFINs is highlighted and depicted by a sequence logo. Grey arrows: common conserved cysteine residues; black arrows: sub-type specific cysteine residues; SP: signal peptide; PEXEL: Plasmodium export element; C1: semi-conserved domain, including the 25 AA insertion/deletion; C2: C-terminal conserved domain; TM1 and TM2: previously predicted transmembrane regions; V1: first variable domain; V2: second variable domain.

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