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Figure 3 | BMC Genomics

Figure 3

From: Identification of Pou5f1, Sox2, and Nanog downstream target genes with statistical confidence by applying a novel algorithm to time course microarray and genome-wide chromatin immunoprecipitation data

Figure 3

Comparison of gene expression responses to suppression of Pou5f1 and Sox2: (A) number of genes with > 2 fold change in gene expression after suppression of Pou5f1 and Sox2; (B) proportion of genes with consistent responses (i.e., common genes whose expression changed in the same direction) and inconsistent responses (i.e., common genes whose expression changed in the opposite direction) to Pou5f1 and Sox2 suppression among the combined list of genes that responded by > 2 fold to either of these transcription factors; (C-D) Principal Component Analysis (PCA) of gene expression response to the suppression of Pou5f1 and Sox2 based on combined data.

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BMC Genomics

ISSN: 1471-2164

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