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Table 7 Ratio criterion sequences in indirect gene category

From: Microarray analysis of the in vivo sequence preferences of a minor groove binding drug

5-mer

Indirectly Affected

Ratio

6-mer

Indirectly Affected

Ratio

aatct

9

3.3

cattct

5

20.0

aacaa

16

2.7

ctgaaa

5

10.0

caaca

8

2.5

taagga

5

10.0

caata

8

2.3

aacaac

5

5.0

aatac

8

2.1

acaaca

5

5.0

tctct

9

2.1

tataag

7

3.5

acaca

8

2.0

aaacca

5

3.3

tataa

17

2.0

aataca

5

3.3

ataag

8

1.8

tctttc

5

3.3

gaata

9

1.6

aaacaa

9

3.0

  1. Sequences ranked according to the number of occurrence in upstream regions of genes hypothesized to be indirectly affected compared to unaffected genes. The number of occurrences in affected genes and ratio of occurrences in affected genes to unaffected genes is listed for each sequence. Bolded sequences are shared with Table 6.