Figure 4From: The mitochondrial genome of the hexactinellid sponge Aphrocallistes vastus: Evidence for programmed translational frameshiftingFrameshifts in the cox3 and nad6 genes. The genes cox3 (A) and nad6 (B) in the A. vastus mtDNA both contain +1 frameshifts at the rare tryptophan codon UGG. After the UGG, the amino acid sequence of first frame (blue shading) becomes degenerate and reaches a premature stop codon. Multiple alignment of these genes from closely- and distantly-related animal taxa reveal conservation of the amino acid sequence in the +1 frame (pink shading), achieved by shifting from the codon UGG to GGA (boxes).Back to article page