Figure 1

Histograms derived from Gene Set Enrichment Analysis for categories with a corrected p-value ≤ 0.0004. A) Density versus t-value plots for protein biogenesis, stress response, unknown, carbohydrate metabolism, and RNA processing categories. Red lines represent the distribution of genes of a specific category in the array. Black lines represent the distribution of all genes in the array. B) t-value versus A-value plots for protein biogenesis, stress response, unknown, carbohydrate metabolism, and RNA processing categories. Red dots represent the genes of a specific category in the array. Black dots represent the distribution of all genes in the array. The cutoff for a significant category is based on a p-value calculated after 10,000 permutations and then a corrected p-value was calculated using the Bonferroni correction. See Methods section for details.