Figure 7

Part of the networks downsteam of RUNX1. Additional data from the literature and our studies were used to update the standard Ingenuity Pathway System (Ingenuity^® Systems, http://www.ingenuity.com) network analyses. Genes up-regulated (red) or down-regulated (green) in either FPD or CBF are indicated. Selected chosen functions with significant network nodes are shown including all the genes involved in cytoskeleton organization. Grey arrows represent transcriptional regulation, grey lines represent direct interaction, dotted lines represent indirect link. Each kind of molecule is represented by a different symbol (see http://www.ingenuity.com).