Figure 1

Schematic representation of three regions of the B. saltans genome sequence, as shown in the Artemis genome browser. Six reading frames are shown as parallel grey bars; scale in base-pairs. Base composition is plotted above. Putative coding sequences are shown as coloured boxes: red (homolog of trypanosomatid gene with known function), orange (homolog of hypothetical trypanosomatid gene), green (hypothetical gene with no trypanosomatid homolog but a positive functional match to a sequence database), blue (hypothetical gene with no matches to sequence databases). Labels attending these coding sequences contain the GeneDB identification numbers of homologous trypanosomatid genes where possible, or the description of homologous genes detected by BLAST comparisons (with % identity). Predicted transmembrane helices (blue) and signal peptides (purple) are shown on the DNA strands below the coding sequence. a. Clone '16k02' containing a tandem gene array of heat-shock protein 70. b. Clone '14l17' containing a tandem gene array of α- and β-tubulin. An asterisk * denotes a β-tubulin gene disrupted by a single base deletion at position 589. c. Clone '5m18' containing a second tandem gene array of α- and β-tubulin.